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2021
- A systems-based method to repurpose marketed therapeutics for antiviral use: A SARS-CoV-2 case study
Mengran Wang, Johanna Withers, Piero Ricchiuto, Ivan Voitalov, Michael McAnally, Helia Sanchez, Alif Saleh, Viatcheslav Akmaev, and Susan Ghiassian
-
Mechanistic Insights into a CDK9 inhibitor via orthogonal Proteomics Methods
J. Adam Hendricks,
- Nigel Beaton*,
- Alexey Chernobrovkin,
- Eric Miele,
- Ghaith M. Hamza,
- Piero Ricchiuto,
- Ronald C. Tomlinson,
- Tomas Friman,
- Cassandra Borenstain,
- Bernard Barlaam,
- Sudhir Hande,
- Michelle L. Lamb,
- Chris De Savi,
- Rick Davies,
- Martin Main,
- Joakim Hellner,
- Kristina Beeler,
- Yuehan Feng,
- Roland Bruderer,
- Lukas Reiter,
- Daniel Martinez Molina*, and
- M. Paola Castaldi*
2019
- Phenotypic Screen with the Human Secretome Identifies FGF16 as inducing Proliferation of iPSC-Derived Cardiac Progenitor Cells
Karin Jennbacken, Fredrik Wågberg, Ulla Karlsson, Jerry Eriksson, Lisa Magnusson, Marjorie Chimienti, Piero Ricchiuto, Jenny Bernström, Mei Ding, Douglas Ross-Thriepland, Yafeng Xue, Diluka Peiris, Teodor Aastrup, Hanna Tegel , Sophia Hober, Åsa Sivertsson, Mathias Uhlén, Per-Erik Strömstedt, Rick Davies and Lovisa Holmberg Schiavone
Int. J. Mol. Sci. 2019, 20(23), 6037; DOI: https://doi.org/10.3390/ijms202360
2018
- Human iPS-derived astroglia from a stable neural precursor state improved functionality compared to conventional astrocytic models
Lundin A, Delsing L, Clausen M, Ricchiuto P, Sanchez J, Sabirsh A, Ding M, Synnergren J, Zetterberg H, Brolén G, Hicks R, Herland A, Falk A.
Stem Cell Reports DOI:10.1016/j.stemcr.2018.01.021
- Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC to provide insight into small molecular targeting of BCL6
Chemical Biology DOI: 10.1021/acschembio.8b00698
2017
- DOSCHEDA: a web application for interactive chemoproteomics data analysis
Bruno Contrino, Eric Miele, Ronald Tomlinson, M. Paola Castaldi, Piero Ricchiuto
PeerJ Computer Science
DOI:10.7717/peerj-cs.129
- Book ARMC: Platform Technologies in Drug Discovery and Validation volume 50, Chemical Biology
M.P. Castaldi, 1, Andrea Zuhl, Piero Ricchiuto, Adam Hendricks
Link to the book
2016
- Endophenotype Network Models: Common Core of Complex Diseases
Susan Dina Ghiassian, Jörg Menche, Daniel I. Chasman, Franco Giulianini, Ruisheng Wang, Piero Ricchiuto, Masanori Aikawa, Hiroshi Iwata, Christian Müller , Tania Zeller, Amitabh Sharma, Sasha Singh, Paul M Ridker, Stefan Blankenberg, Albert-László Barabási, and Joseph Loscalzo
Nature Scientific Reports 6, 27414 (2016)
- PARP9 and PARP14 cross-regulated macrophage activation via STAT1 ADP-ribolsylaiton (Nature Comm. in press)
Hiroshi Iwata, Claudia Goettsch, Amitabh Sharma, Piero Ricchiuto, Wilson Wen Bin Goh, Arda Halu, Iwao Yamada, Hideo Yoshida, Takuya Hara, Mei Wei, Noriyuki Inoue,Daiju Fukuda, Alexander Mojcher, Peter C. Mattson, Albert-László Barabási,Mark Boothby, Elena Aikawa, Sasha A. Singh, and Masanori Aikawa
Nature Communication 7,12849(2016)
2015
- Analyzing extremely small sized ratio datasets
P. Ricchiuto et al.
Int. J. Bioinformatics Research and Applications, Vol. 11, No. 3, 2015
- mTMT-visHTS: A novel method for multiplexing TMT datasets with a tunable accompanying visualization high throughput screening tool for protein profiling.
P. Ricchiuto, H.Iwata et al.
Journal of Proteomics 2015
2012
- Two-step nucleation of amyloid fibrils: omnipresent or not?
S. Auer, P. Ricchiuto and D. Kashchiev
J. Mol. Biol. 2012
- Tracking polypeptide folds on the free energy surface: effects of the chain length and sequence
A. Brukhno, P. Ricchiuto, and S. Auer.
J Phys Chem B 2012
- Protein aggregation: kinetics vs thermodynamic.
P. Ricchiuto, A. Brukhno, and S. Auer.
J. Phys. Chem. B, 2012
2011
- Conformation state diagram of polypeptides: a chain length induced α-β transition.
P. Ricchiuto, A. Brukhno, E. Paci and S. Auer.
J. Chem. Phys. 135, 061101 (2011)
- Simulation of urea-induced protein unfolding: A lesson from BOVINE β-lactoglobulin.
Eberini, I., Emerson, A., Sensi, C., Ragona, L., Ricchiuto, P., Pedretti, A., Gianazza, E. and Tramontano, A. .
Journal of Molecular Graphics and Modelling
2010
- Nephrocystin-1 Forms a Complex with Polycystin-1 via a Polyproline Motif/SH3 Domain Interaction and Regulates the Apoptotic Response in Mammals.
Claas Wodarczyk, Gianfranco Distefano, Isaline Rowe, Massimiliano Gaetani, Barbara Bricoli, Mordi Muorah, Andrea Spitaleri, Valeria Mannella, Piero Ricchiuto, Monika Pema, Maddalena Castelli, Ariel E. Casanova, Luca Mollica, Manuela Banzi, Manila Boca, Corinne Antignac, Sophie Saunier, Giovanna Musco, Alessandra Boletta
PLoS ONE 5(9)
2008
- Structural and dynamic roles of permanent water molecules in ligand molecular recognition by chicken liver bile acid binding protein.
Piero Ricchiuto, Alessandro Guerini Rocco, ElisabettaGianazza, Dario Corrada, Tiziana Beringhelli and Ivano Eberini
J Mol Recognit. 2008
- Characterization of the protein unfolding process induced by urea and temperature.
Alessandro Guerini Rocco, Luca Mollica, Piero Ricchiuto, António M. Baptista, Elisabetta Gianazza and Ivano Eberini
2005
- Pigment epithelium-derived factor is differentially expressed in peripheral neuropathies.
Antonio Conti, Piero Ricchiuto, Sandro Iannaccone, Barbara Sferrazza, Angela Cattaneo, Angela Bachi, Angelo Reggiani, Massimiliano Beltramo, Massimo Alessio
J. Proteomics
Papers Contributions
2020
- Idiopathic pulmonary fibrosis: airway volume measurement identifies progressive disease on computed tomography scans
Contribution here
2014
- Co-regulation proteomics revelas substrates and mechanisms of APC/C-dependent degradation
Singh SA, Winter D, Kirchner M, Chauhan R, Ahmed S, Ozlu N, Tzur A, Steen JA, Steen H
DOI: 10.1002/embj.201385876
2013
- Cystathionine y-lyase Accelerates Oscteoclast Differentiation: Identification of a Novel Regulator of Osteoclastogenesis by Proteomic Analysis
Takahiro Itou, Natalia Maldonado, Iwao Yamada, Claudia Goettsch, Jiro Matsumoto, Masanori Aikawa, Sasha Singh, Elena Aikawa
DOI: 10.1161/ATVBAHA.113.302576
Patents
- PARP9 and PARP14 are novel regulators of macrophage activation (filed 2015, USA)
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Publications
